Fuhai Li, PhD

Assistant Professor of Pediatrics
School of Medicine

Fuhai Li, PhD, is focused on applying statistical, machine learning, deep learning and data mining approaches on diverse biomedical dataset integration and interpretation, to solve the challenges in  bioinformatics, systems biology and image informatics.


Fuhai Li, PhD, is an Assistant Professor at the Institute for Informatics and Department of Pediatrics at Washington University School of Medicine in St. Louis. His recent research has focused on the integration and interpretation of diverse and heterogeneous pharmacogenomics data for i) understanding driver genetics/functional (mechanism), ii) discovering novel combinatory therapies to overcome intrinsic/acquired drug resistance (with reduced toxicity and synergy effects), and iii) uncovering and perturbing the tumor-stroma interaction to understand the roles of tumor micro-environment/niche in disease development.

Dr. Li obtained his PhD in Applied Math from Peking University. Then he conducted research as a visiting scholar at Harvard Medical School (HMS)/Brigham Women’s Hospital (BWH), where his research focused on developing computational approaches of bio-image informatics to automatically quantify thousands of cellular images to identify potential drugs and targets that can perturb cell cycles and cellular phenotypes. Prior to joining the faculty at Washington University, Dr. Li was an Assistant Professor in the Biomedical Informatics Department at The Ohio State University.

Research Interests

  • Integrative large-scale pharmaco genomics analysis for target, signaling network, drug and drug combination discovery
  • Genomics data driven tumor-stromal communication discovery and modeling

Lab Members

  • Jielin Xu, PhD, Post-Doctoral Fellow, Washington University School of Medicine in St. Louis, Institute for Informatics
  • Tianyu Zhang, Visiting Student Scholar, Washington University School of Medicine in St. Louis, Institute for Informatics